So much for the talk all week from the Dallas Cowboys about finding a way get receiver George Pickens more involved in the offense heading into Sunday’s desperation must-win game vs. the Indianapolis Colts.

Pickens was one of seven players made inactive for the game. He was limited in practice all week with a hamstring injury. He was on the injury report last week with a shoulder injury.

The other inactives include linebacker DeMarvion Overshown, cornerback Joey Porter Jr., kick returner KaVontae Turpin, edge rusher Tyrus Wheat, offensive lineman Ajani Cornelius and tight end Luke Schoonmaker.

At 3-5, the Cowboys must beat the Colts (2-6) to keep their diminishing playoff hopes alive.

That job became tougher with Pickens on sideline as well as their best cornerback in Porter and Overshown, who has been their most impactful linebacker since returning to the lineup two games ago after missing fives games with a hamstring injury.

Pickens is the team’s second leading receiver behind CeeDee Lamb but has been limited to 39 catches for 533 yards and two touchdowns through the first eight games.

It’s all a huge setback for Pickens, who came into the season looking to build off his 2025 campaign when he led the Cowboys in yards, catches and touchdowns and parlay it into a big-money contract extension at the end of the season.

Pickens is playing the 2025 season on the franchise tag for roughly $27 million.